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How Numbers, Nature, and Immune Status of Foxp3(+) Regulatory T-Cells Shape the Early Immunological Events in Tumor Development

The influence of CD4(+)CD25(+)Foxp3(+) regulatory T-cells (Tregs) on cancer progression has been demonstrated in a large number of preclinical models and confirmed in several types of malignancies. Neoplastic processes trigger an increase of Treg numbers in draining lymph nodes, spleen, blood, and t...

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Detalhes bibliográficos
Main Authors: Darrasse-Jèze, Guillaume, Podsypanina, Katrina
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784046/
https://ncbi.nlm.nih.gov/pubmed/24133490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2013.00292
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