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Environmental and genetic activation of a brain-adipocyte BDNF/leptin axis causes cancer remission and inhibition

Cancer is influenced by its microenvironment, yet broader, environmental effects also play a role but remain poorly defined. We report here that mice living in an enriched housing environment show reduced tumor growth and increased remission. We found this effect in melanoma and colon cancer models,...

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Detalhes bibliográficos
Main Authors: Cao, Lei, Liu, Xianglan, Lin, En-Ju D., Wang, Chuansong, Choi, Eugene Y., Riban, Veronique, Lin, Benjamin, During, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3784009/
https://ncbi.nlm.nih.gov/pubmed/20603014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.05.029
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