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Targeting cardiac β-adrenergic signaling via GRK2 inhibition for heart failure therapy

Cardiac cells, like those of the other tissues, undergo regulation through membrane-bound proteins known as G protein-coupled receptors (GPCRs). β-adrenergic receptors (βARs) are key GPCRs expressed on cardiomyocytes and their role is crucial in cardiac physiology since they regulate inotropic and c...

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Autors principals: Cannavo, Alessandro, Liccardo, Daniela, Koch, Walter J.
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783981/
https://ncbi.nlm.nih.gov/pubmed/24133451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00264
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