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Targeting cardiac β-adrenergic signaling via GRK2 inhibition for heart failure therapy
Cardiac cells, like those of the other tissues, undergo regulation through membrane-bound proteins known as G protein-coupled receptors (GPCRs). β-adrenergic receptors (βARs) are key GPCRs expressed on cardiomyocytes and their role is crucial in cardiac physiology since they regulate inotropic and c...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Frontiers Media S.A.
2013
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783981/ https://ncbi.nlm.nih.gov/pubmed/24133451 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2013.00264 |
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