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Targeted ablation of the PTH/PTHrP receptor in osteocytes impairs bone structure and homeostatic calcemic responses

Parathyroid hormone (PTH) is a major physiologic regulator of calcium, phosphorous and skeletal homeostasis. Cells of the osteoblastic lineage are key targets of PTH action in bone, and recent evidence suggests that osteocytes might be important in the anabolic effects of PTH. To understand the role...

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Autori principali: Powell, William F., Barry, Kevin J., Tulum, Irena, Kobayashi, Tatsuya, Harris, Stephen E., Bringhurst, F. Richard, Pajevic, Paola Divieti
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783949/
https://ncbi.nlm.nih.gov/pubmed/21220409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/JOE-10-0308
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