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An important role for Cholecystokinin, a CLOCK target gene, in the development and treatment of manic-like behaviors
Mice with a mutation in the Clock gene (ClockΔ19) have been identified as a model of mania, however, the mechanisms that underlie this phenotype, and the changes in the brain that are necessary for lithium’s effectiveness on these mice remain unclear. Here we find that Cholecystokinin(Cck) is a dire...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3783638/ https://ncbi.nlm.nih.gov/pubmed/23399917 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mp.2013.12 |
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