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Response to a Single Dose of Sildenafil in Single-Ventricle Patients: An Echocardiographic Evaluation

New evidence of increased phosphodiesterase-5 (PDE-5) in hypertrophied human myocardium suggests that sildenafil, a selective PDE-5 inhibitor, may improve muscle contraction and therefore improve ventricular function. The purpose of this study was to compare ventricular function as assessed by echoc...

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Hlavní autoři: Jackson, Kimberly W., Butts, Ryan J., Svenson, Amy J., McQuinn, Tim C., Atz, Andrew M.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783569/
https://ncbi.nlm.nih.gov/pubmed/22806713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00246-012-0415-4
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