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MiR-27a Regulates Apoptosis in Nucleus Pulposus Cells by Targeting PI3K

The precise role of apoptosis in the pathogenesis of intervertebral disc degeneration (IDD) remains to be elucidated. We analyzed degenerative nucleus pulposus (NP) cells and found that the expression of miR-27a was increased. The overexpression of miR-27a was further verified using real-time RT-PCR...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Gang, Cao, Peng, Chen, Huajiang, Yuan, Wen, Wang, Jianxi, Tang, Xianye
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783482/
https://ncbi.nlm.nih.gov/pubmed/24086481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075251
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