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MiR-27a Regulates Apoptosis in Nucleus Pulposus Cells by Targeting PI3K

The precise role of apoptosis in the pathogenesis of intervertebral disc degeneration (IDD) remains to be elucidated. We analyzed degenerative nucleus pulposus (NP) cells and found that the expression of miR-27a was increased. The overexpression of miR-27a was further verified using real-time RT-PCR...

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Detalhes bibliográficos
Main Authors: Liu, Gang, Cao, Peng, Chen, Huajiang, Yuan, Wen, Wang, Jianxi, Tang, Xianye
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783482/
https://ncbi.nlm.nih.gov/pubmed/24086481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075251
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