Aquaporin 5 regulates cigarette smoke induced emphysema by modulating barrier and immune properties of the epithelium

Chronic obstructive pulmonary disease (COPD) causes significant morbidity and mortality. Cigarette smoke, the most common risk factor for COPD, induces airway and alveolar epithelial barrier permeability and initiates an innate immune response. Changes in abundance of aquaporin 5 (AQP5), a water cha...

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Hauptverfasser: Aggarwal, Neil R., Chau, Eric, Garibaldi, Brian T., Mock, Jason R., Sussan, Thomas, Rao, Keshav, Rao, Kaavya, Menon, Anil G., D’Alessio, Franco R., Damarla, Mahendra, Biswal, Shyam, King, Landon S., Sidhaye, Venkataramana K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2013
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783223/
https://ncbi.nlm.nih.gov/pubmed/24665410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/tisb.25248
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