PP1α, PP1β and Wip-1 regulate H4S47 phosphorylation and deposition of histone H3 variant H3.3

Phosphorylation of histone H4 serine 47 (H4S47ph) is catalyzed by Pak2, a member of the p21-activated serine/threonine protein kinase (Pak) family and regulates the deposition of histone variant H3.3. However, the phosphatase(s) involved in the regulation of H4S47ph levels was unknown. Here, we show...

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Bibliographic Details
Main Authors: Zhang, Hui, Wang, Zhiquan, Zhang, Zhiguo
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
Subjects:
Gene Regulation, Chromatin and Epigenetics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783166/
https://ncbi.nlm.nih.gov/pubmed/23828041
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt583
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