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Co-inhibition of Plasmodium falciparum S-Adenosylmethionine Decarboxylase/Ornithine Decarboxylase Reveals Perturbation-specific Compensatory Mechanisms by Transcriptome, Proteome, and Metabolome Analyses()

Polyamines are ubiquitous components of all living cells, and their depletion usually causes cytostasis, a strategy employed for treatment of West African trypanosomiasis. To evaluate polyamine depletion as an anti-malarial strategy, cytostasis caused by the co-inhibition of S-adenosylmethionine dec...

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Bibliografiska uppgifter
Huvudupphovsmän: van Brummelen, Anna C., Olszewski, Kellen L., Wilinski, Daniel, Llinás, Manuel, Louw, Abraham I., Birkholtz, Lyn-Marie
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Biochemistry and Molecular Biology 2009
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3783055/
https://ncbi.nlm.nih.gov/pubmed/19073607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807085200
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