Altered Contractile Phenotypes of Intestinal Smooth Muscle in Mice Deficient in Myosin Phosphatase Target Subunit 1

BACKGROUND & AIMS: The regulatory subunit of myosin light chain phosphatase, MYPT1, has been proposed to control smooth muscle contractility by regulating phosphorylation of the Ca(2+)-dependent myosin regulatory light chain. We generated mice with a smooth muscle–specific deletion of MYPT1 to i...

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Autors principals: He, Wei–Qi, Qiao, Yan–Ning, Peng, Ya–Jing, Zha, Juan–Min, Zhang, Cheng–Hai, Chen, Chen, Chen, Cai–Ping, Wang, Pei, Yang, Xiao, Li, Chao–Jun, Kamm, Kristine E., Stull, James T., Zhu, Min–Sheng
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782749/
https://ncbi.nlm.nih.gov/pubmed/23499953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2013.02.045
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