Ciclosporin does not attenuate intracranial hypertension in rats with acute hyperammonaemia

AIM: To investigate the neuroprotective potential of ciclosporin during acute liver failure. We evaluated the effect of intrathecally administered ciclosporin on intracranial pressure, brain water content and aquaporin-4 expression in a rat model with acute hyperammonaemia. METHODS: Twenty-four male...

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Autors principals: Larsen, Rikke Hebo, Kjær, Mette S, Eefsen, Martin, Larsen, Fin Stolze, Bjerring, Peter Nissen
Format: Artigo
Idioma:Inglês
Publicat: Baishideng Publishing Group Co., Limited 2013
Matèries:
Brief Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782689/
https://ncbi.nlm.nih.gov/pubmed/24073303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4254/wjh.v5.i9.513
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