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Interferon γ-induced intratumoral expression of CXCL9 alters the local distribution of T cells following immunotherapy with Listeria monocytogenes

The ability of Listeria monocytogenes-based anticancer vaccines to induce tumor regression depends on the responsiveness of malignant cells to interferon γ (IFNγ). Inhibition of IFNγ limits the recruitment of T cells to the tumors of vaccinated mice. We hypothesized that vaccination with immunothera...

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Bibliografische gegevens
Hoofdauteurs: Guirnalda, Patrick, Wood, Laurence, Goenka, Radhika, Crespo, Joel, Paterson, Yvonne
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Landes Bioscience 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782529/
https://ncbi.nlm.nih.gov/pubmed/24083082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.25752
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