HIF1A Reduces Acute Lung Injury by Optimizing Carbohydrate Metabolism in the Alveolar Epithelium

BACKGROUND: While acute lung injury (ALI) contributes significantly to critical illness, it resolves spontaneously in many instances. The majority of patients experiencing ALI require mechanical ventilation. Therefore, we hypothesized that mechanical ventilation and concomitant stretch-exposure of p...

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Detalhes bibliográficos
Main Authors: Eckle, Tobias, Brodsky, Kelley, Bonney, Megan, Packard, Thomas, Han, Jun, Borchers, Christoph H., Mariani, Thomas J., Kominsky, Douglas J., Mittelbronn, Michel, Eltzschig, Holger K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782424/
https://ncbi.nlm.nih.gov/pubmed/24086109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.1001665
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