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Obesity in mice with adipocyte-specific deletion of clock component Arntl

Adipocytes store excess energy in the form of triglycerides and signal the levels of stored energy to the brain. Here we show that adipocyte-specific deletion of Arntl (also known as Bmal1), a gene encoding a core molecular clock component, results in obesity in mice with a shift in the diurnal rhyt...

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Detalhes bibliográficos
Main Authors: Paschos, Georgios K, Ibrahim, Salam, Song, Wen-Liang, Kunieda, Takeshige, Grant, Gregory, Reyes, Teresa M, Bradfield, Christopher A, Vaughan, Cheryl H, Eiden, Michael, Masoodi, Mojgan, Griffin, Julian L, Wang, Fenfen, Lawson, John A, FitzGerald, Garret A
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782286/
https://ncbi.nlm.nih.gov/pubmed/23142819
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2979
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