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Double-stranded RNA binding by the human cytomegalovirus PKR antagonist TRS1
Protein Kinase R (PKR) inhibits translation initiation following double-stranded RNA (dsRNA) binding and thereby represses viral replication. Human cytomegalovirus (HCMV) encodes two noncanonical dsRNA binding proteins, IRS1 and TRS1, and the expression of at least one of these PKR antagonists is es...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3782281/ https://ncbi.nlm.nih.gov/pubmed/23601785 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.03.024 |
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