Degradation of Host MicroRNAs by Poxvirus Poly(A) Polymerase Reveals Terminal RNA Methylation as a Protective Antiviral Mechanism

The life cycle of several viruses involves host or virally encoded small noncoding RNAs, which play important roles in posttranscriptional regulation. Small noncoding RNAs include microRNAs (miRNAs), which modulate the transcriptome, and small interfering RNAs (siRNAs), which are involved in pathoge...

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Bibliografiske detaljer
Main Authors: Backes, Simone, Shapiro, Jillian S., Sabin, Leah R., Pham, Alissa M., Reyes, Ismarc, Moss, Bernard, Cherry, Sara, tenOever, Benjamin R.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782087/
https://ncbi.nlm.nih.gov/pubmed/22901540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.05.019
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