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Degradation of Host MicroRNAs by Poxvirus Poly(A) Polymerase Reveals Terminal RNA Methylation as a Protective Antiviral Mechanism

The life cycle of several viruses involves host or virally encoded small noncoding RNAs, which play important roles in posttranscriptional regulation. Small noncoding RNAs include microRNAs (miRNAs), which modulate the transcriptome, and small interfering RNAs (siRNAs), which are involved in pathoge...

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Detalhes bibliográficos
Main Authors: Backes, Simone, Shapiro, Jillian S., Sabin, Leah R., Pham, Alissa M., Reyes, Ismarc, Moss, Bernard, Cherry, Sara, tenOever, Benjamin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782087/
https://ncbi.nlm.nih.gov/pubmed/22901540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2012.05.019
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