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MALDI imaging and in situ identification of integral membrane proteins from rat brain tissue sections

Transmembrane proteins are greatly underrepresented in data generated by imaging mass spectrometry (IMS) because of analytical challenges related to their size and solubility. Here we present the first example of MALDI IMS of two highly modified multi-transmembrane domain proteins, myelin proteolipi...

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Autors principals: Nicklay, Joshua J., Harris, Glenn A., Schey, Kevin L., Caprioli, Richard M.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782084/
https://ncbi.nlm.nih.gov/pubmed/23829295
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac400902h
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