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TORC1 Signaling Is Governed by Two Negative Regulators in Fission Yeast

The target of rapamycin (TOR) is a highly conserved protein kinase that regulates cell growth and metabolism. Here we performed a genome-wide screen to identify negative regulators of TOR complex 1 (TORC1) in Schizosaccharomyces pombe by isolating mutants that phenocopy Δtsc2, in which TORC1 signali...

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Detalhes bibliográficos
Main Authors: Ma, Ning, Liu, Qingbin, Zhang, Lili, Henske, Elizabeth P., Ma, Yan
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781973/
https://ncbi.nlm.nih.gov/pubmed/23934889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.113.154674
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