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Global Optimization of the IR Matrix-Assisted Laser Desorption Ionization (IR MALDESI) Source for Mass Spectrometry Using Statistical Design of Experiments

Design of experiments (DOE) is a systematic and cost-effective approach to system optimization by which the effects of multiple parameters and parameter interactions on a given response can be measured in few experiments. Herein, we describe the use of statistical DOE to improve a few of the analyti...

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Detalhes bibliográficos
Main Authors: Barry, Jeremy A., Muddiman, David C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781580/
https://ncbi.nlm.nih.gov/pubmed/22095501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rcm.5262
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