Combination Pravastatin and Valsartan Treatment Has Additive Beneficial Effects to Simultaneously Improve Both Metabolic and Cardiovascular Phenotypes Beyond That of Monotherapy With Either Drug in Patients With Primary Hypercholesterolemia

Statin and angiotensin II type 1 receptor blocker therapy improves endothelial dysfunction using distinct mechanisms. We evaluated simultaneous vascular and metabolic responses to pravastatin and valsartan therapy, alone or in combination, in hypercholesterolemic patients. Forty-eight hypercholester...

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Detalhes bibliográficos
Main Authors: Koh, Kwang Kon, Lim, Soo, Choi, Hanul, Lee, Yonghee, Han, Seung Hwan, Lee, Kyounghoon, Oh, Pyung Chun, Sakuma, Ichiro, Shin, Eak Kyun, Quon, Michael J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2013
Assuntos:
Pathophysiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781478/
https://ncbi.nlm.nih.gov/pubmed/23863812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db13-0566
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