In Silico Design of Optimal Ratio for Co-Administration of Pramlintide and Insulin in Type 1 Diabetes

BACKGROUND: The ability to simulate in silico experiments is crucial for fast and cost-effective preliminary studies prior to clinical trials. We present an in silico approach to the design of optimal pramlintide-to-insulin (P/I) ratios, using our computer simulator of the human metabolic system, wi...

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Main Authors: Micheletto, Francesco, Dalla Man, Chiara, Kolterman, Orville, Chiquette, Elaine, Herrmann, Kathrin, Schirra, Jörg, Kovatchev, Boris, Cobelli, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2013
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781117/
https://ncbi.nlm.nih.gov/pubmed/23865841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/dia.2013.0054
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