Increase in Net Activity of Serine Proteinases but Not Gelatinases after Local Endotoxin Exposure in the Peripheral Airways of Healthy Subjects

We tested the hypothesis that activation of the innate immune response induces an imbalance in the proteolytic homeostasis in the peripheral airways of healthy subjects, towards excess serine or gelatinase proteinase activity. During bronchoscopy, 18 healthy human subjects underwent intra-bronchial...

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Detalhes bibliográficos
Main Authors: Smith, Margaretha E., Bozinovski, Steven, Malmhäll, Carina, Sjöstrand, Margareta, Glader, Pernilla, Venge, Per, Hiemstra, Pieter S., Anderson, Gary P., Lindén, Anders, Qvarfordt, Ingemar
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3781029/
https://ncbi.nlm.nih.gov/pubmed/24086430
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075032
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