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Differential Active Site Loop Conformations Mediate Promiscuous Activities in the Lactonase SsoPox
Enzymes are proficient catalysts that enable fast rates of Michaelis-complex formation, the chemical step and products release. These different steps may require different conformational states of the active site that have distinct binding properties. Moreover, the conformational flexibility of the...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Public Library of Science
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3781021/ https://ncbi.nlm.nih.gov/pubmed/24086491 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075272 |
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