The Purification Method Using Iodixanol (Optiprep)-Based Density Gradient Significantly Reduces Cytokine/Chemokine Production from Human Islet Preparations, Leading to Prolong β-Cell Survival During Culture

Improved islet isolation has still been important to obtain adequate islet numbers for islet transplantation. Although Ficol-based density gradient is widely used for purification in most islet processing centers, OptiPrep-based density gradient is recently used in the limited centers and their clin...

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Главные авторы: Mita, Atsuyoshi, Ricordi, Camillo, Miki, Atsushi, Barker, Scott, Khan, Aisha, Alvarez, Alejandro, Hashikura, Yasuhiko, Miyagawa, Shin-ichi, Ichii, Hirohito
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780973/
https://ncbi.nlm.nih.gov/pubmed/19249543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.transproceed.2008.10.059
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