Pathogenic role of diabetes-induced PPAR-α down-regulation in microvascular dysfunction

Two independent clinical studies have reported that fenofibrate, a peroxisome proliferator-activated receptor α (PPARα) agonist, has robust therapeutic effects on microvascular complications of diabetes, including diabetic retinopathy (DR) in type 2 diabetic patients. However, the expression and fun...

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Main Authors: Hu, Yang, Chen, Ying, Ding, Lexi, He, Xuemin, Takahashi, Yusuke, Gao, Yang, Shen, Wei, Cheng, Rui, Chen, Qian, Qi, Xiaoping, Boulton, Michael E., Ma, Jian-xing
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2013
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780907/
https://ncbi.nlm.nih.gov/pubmed/24003152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307211110
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