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Drift and conservation of differential exon usage across tissues in primate species

Alternative usage of exons provides genomes with plasticity to produce different transcripts from the same gene, modulating the function, localization, and life cycle of gene products. It affects most human genes. For a limited number of cases, alternative functions and tissue-specific roles are kno...

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Détails bibliographiques
Auteurs principaux: Reyes, Alejandro, Anders, Simon, Weatheritt, Robert J., Gibson, Toby J., Steinmetz, Lars M., Huber, Wolfgang
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780897/
https://ncbi.nlm.nih.gov/pubmed/24003148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1307202110
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