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Functional protease profiling with reporter peptides in serum specimens of colorectal cancer patients: demonstration of its routine diagnostic applicability

BACKGROUND: The progression of many solid tumors is characterized by the release of tumor-associated proteases and the detection of tumor specific proteolytic activity in serum specimens is a promising diagnostic tool in oncology. Here we describe a mass spectrometry-based functional proteomic profi...

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Autores principales: Findeisen, Peter, Costina, Victor, Yepes, Diego, Hofheinz, Ralf, Neumaier, Michael
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780806/
https://ncbi.nlm.nih.gov/pubmed/22682081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-9966-31-56
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