Phenotypic Assays For β-Amyloid In Mouse Embryonic Stem Cell-derived Neurons

Given the complex nature of Alzheimer’s disease (AD), a cell-based model that recapitulates physiological properties of the target neuronal population carries significant value in discovering improved drug candidates and chemical probes for uncovering disease mechanisms. We established phenotypic ne...

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Autors principals: McIntire, Laura Beth J., Landman, Natalie, Kang, Min Suk, Finan, Gina, Hwang, Jeremy, Moore, Ann Z., Park, Lydia S., Lin, Chyuan-Sheng, Kim, Tae-Wan
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780781/
https://ncbi.nlm.nih.gov/pubmed/23890013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2013.06.005
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