Aerosol Administration of Phospho-sulindac Inhibits Lung Tumorigenesis

Phospho-sulindac (PS) is a sulindac derivative with promising anticancer activity in lung cancer, but its limited metabolic stability presents a major challenge for systemic therapy. We reasoned that inhalation delivery of PS might overcome first-pass metabolism and produce high levels of intact dru...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Cheng, Ka Wing, Wong, Chi C, Alston, Ninche, Mackenzie, Gerardo G, Huang, Liqun, Ouyang, Nengtai, Xie, Gang, Wiedmann, Timothy, Rigas, Basil
Format: Artigo
Jezik:Inglês
Izdano: 2013
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780561/
https://ncbi.nlm.nih.gov/pubmed/23645590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-13-0006-T
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki