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Estrogen modulates the influence of cardiac inflammatory cells on function of cardiac fibroblasts

BACKGROUND: Inflammatory cells play a major role in the pathology of heart failure by stimulating cardiac fibroblasts to regulate the extracellular matrix in an adverse way. In view of the fact that inflammatory cells have estrogen receptors, we hypothesized that estrogen provides cardioprotection b...

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Hlavní autoři: Mclarty, Jennifer L, Li, Jianping, Levick, Scott P, Janicki, Joseph S
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3780290/
https://ncbi.nlm.nih.gov/pubmed/24062614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JIR.S48422
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