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Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo

MicroRNAs (miRNAs) regulate gene expression by pairing to complementary sequences in the 3’UTRs of transcripts. Though the molecular mechanism underlying miRNA biogenesis and activity is becoming better understood, determining the physiological role of the interaction of a miRNA with its target rema...

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Bibliografiske detaljer
Main Authors: Staton, Alison A., Giraldez, Antonio J.
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779896/
https://ncbi.nlm.nih.gov/pubmed/22134127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.423
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