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Use of target protector morpholinos to analyze the physiological roles of specific miRNA-mRNA pairs in vivo

MicroRNAs (miRNAs) regulate gene expression by pairing to complementary sequences in the 3’UTRs of transcripts. Though the molecular mechanism underlying miRNA biogenesis and activity is becoming better understood, determining the physiological role of the interaction of a miRNA with its target rema...

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Detalhes bibliográficos
Main Authors: Staton, Alison A., Giraldez, Antonio J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779896/
https://ncbi.nlm.nih.gov/pubmed/22134127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2011.423
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