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Histone Methylation at H3K9; Evidence for a Restrictive Epigenome in Schizophrenia

OBJECTIVE: Epigenetic changes are stable and long-lasting chromatin modifications that regulate genomewide and local gene activity. The addition of two methyl groups to the 9(th) lysine of histone 3 (H3K9me2) by histone methyltransferases (HMT) leads to a restrictive chromatin state, and thus reduce...

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Autores principales: Chase, Kayla A., Gavin, David P., Guidotti, Alessandro, Sharma, Rajiv P.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779891/
https://ncbi.nlm.nih.gov/pubmed/23815974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2013.06.021
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