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Histone Methylation at H3K9; Evidence for a Restrictive Epigenome in Schizophrenia

OBJECTIVE: Epigenetic changes are stable and long-lasting chromatin modifications that regulate genomewide and local gene activity. The addition of two methyl groups to the 9(th) lysine of histone 3 (H3K9me2) by histone methyltransferases (HMT) leads to a restrictive chromatin state, and thus reduce...

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書誌詳細
主要な著者: Chase, Kayla A., Gavin, David P., Guidotti, Alessandro, Sharma, Rajiv P.
フォーマット: Artigo
言語:Inglês
出版事項: 2013
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779891/
https://ncbi.nlm.nih.gov/pubmed/23815974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2013.06.021
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