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Histone Methylation at H3K9; Evidence for a Restrictive Epigenome in Schizophrenia
OBJECTIVE: Epigenetic changes are stable and long-lasting chromatin modifications that regulate genomewide and local gene activity. The addition of two methyl groups to the 9(th) lysine of histone 3 (H3K9me2) by histone methyltransferases (HMT) leads to a restrictive chromatin state, and thus reduce...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3779891/ https://ncbi.nlm.nih.gov/pubmed/23815974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.schres.2013.06.021 |
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