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Bone-derived mesenchymal stromal cells from HIV transgenic mice exhibit altered proliferation, differentiation capacity and paracrine functions along with impaired therapeutic potential in kidney injury

Mesenchymal stem cells (MSCs) secrete paracrine factors that could be cytoprotective and serve roles in immunoregulation during tissue injury. Although MSCs express HIV receptors, and co-receptors, and are susceptible to HIV infection, whether HIV-1 may affect biological properties of MSCs needs mor...

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Detalhes bibliográficos
Main Authors: Cheng, Kang, Rai, Partab, Lan, Xiqian, Plagov, Andrei, Malhotra, Ashwani, Gupta, Sanjeev, Singhal, Pravin C
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779877/
https://ncbi.nlm.nih.gov/pubmed/23806280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexcr.2013.06.008
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