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Rhamnetin and Cirsiliol Induce Radiosensitization and Inhibition of Epithelial-Mesenchymal Transition (EMT) by miR-34a-mediated Suppression of Notch-1 Expression in Non-small Cell Lung Cancer Cell Lines

Radioresistance is a major cause of decreasing the efficiency of radiotherapy for non-small cell lung cancer (NSCLC). To understand the radioresistance mechanisms in NSCLC, we focused on the radiation-induced Notch-1 signaling pathway involved in critical cell fate decisions by modulating cell proli...

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Main Authors: Kang, JiHoon, Kim, EunGi, Kim, Wanyeon, Seong, Ki Moon, Youn, HyeSook, Kim, Jung Woo, Kim, Joon, Youn, BuHyun
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779729/
https://ncbi.nlm.nih.gov/pubmed/23902763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.490482
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