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Mapping peptide thiol accessibility in membranes using a quaternary ammonium isotope-coded mass tag (ICMT)

The plasma membrane contains a diverse array of proteins, including receptors, channels, and signaling complexes, that serve as decision-making centers. Investigation of membrane protein topology is important for understanding the function of these types of protein. Here, we report a method to deter...

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Autors principals: Su, Chiao-Yung, London, Erwin, Sampson, Nicole S.
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779509/
https://ncbi.nlm.nih.gov/pubmed/23725486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc400171j
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