Doxorubicin-Induced Vascular Toxicity – Targeting Potential Pathways May Reduce Procoagulant Activity

INTRODUCTION: Previous study in mice using real-time intravital imaging revealed an acute deleterious effect of doxorubicin (DXR) on the gonadal vasculature, as a prototype of an end-organ, manifested by a reduction in blood flow and disintegration of the vessel wall. We hypothesized that this patte...

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Detalhes bibliográficos
Main Authors: Ben Aharon, Irit, Bar Joseph, Hadas, Tzabari, Moran, Shenkman, Boris, Farzam, Nahid, Levi, Mattan, Shalgi, Ruth, Stemmer, Salomon M., Savion, Naphtali
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779248/
https://ncbi.nlm.nih.gov/pubmed/24073244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075157
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