Secreted Human Adipose Leptin Decreases Mitochondrial Respiration in HCT116 Colon Cancer Cells

Obesity is a key risk factor for the development of colon cancer; however, the endocrine/paracrine/metabolic networks mediating this connection are poorly understood. Here we hypothesize that obesity results in secreted products from adipose tissue that induce malignancy-related metabolic alteration...

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Bibliografiske detaljer
Main Authors: Yehuda-Shnaidman, Einav, Nimri, Lili, Tarnovscki, Tanya, Kirshtein, Boris, Rudich, Assaf, Schwartz, Betty
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779244/
https://ncbi.nlm.nih.gov/pubmed/24073224
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0074843
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