Identification of the Sites of Tau Hyperphosphorylation and Activation of Tau Kinases in Synucleinopathies and Alzheimer’s Diseases

OBJECTIVE: Most neurodegenerative diseases contain hyperphosphorylated Tau [p-Tau]. We examined for the first time epitopes at which Tau is hyperphosphorylated in Parkinson’s disease, dementia with Lewy bodies and Alzheimer’s disease, and also select Tau kinases. METHODS: Postmortem frontal cortex f...

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Detalhes bibliográficos
Main Authors: Duka, Valeriy, Lee, Jae-Hoon, Credle, Joel, Wills, Jonathan, Oaks, Adam, Smolinsky, Ciaran, Shah, Ketul, Mash, Deborah C., Masliah, Eliezer, Sidhu, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779212/
https://ncbi.nlm.nih.gov/pubmed/24073234
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075025
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