The Duration of Chlamydia muridarum Genital Tract Infection and Associated Chronic Pathological Changes Are Reduced in IL-17 Knockout Mice but Protection Is Not Increased Further by Immunization

IL-17 is believed to be important for protection against extracellular pathogens, where clearance is dependent on neutrophil recruitment and local activation of epithelial cell defences. However, the role of IL-17 in protection against intracellular pathogens such as Chlamydia is less clear. We have...

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Autores principales: Andrew, Dean W., Cochrane, Melanie, Schripsema, Justin H., Ramsey, Kyle H., Dando, Samantha J., O’Meara, Connor P., Timms, Peter, Beagley, Kenneth W.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2013
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779189/
https://ncbi.nlm.nih.gov/pubmed/24073293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0076664
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