Lipid Metabolites Enhance Secretion Acting on SNARE Microdomains and Altering the Extent and Kinetics of Single Release Events in Bovine Adrenal Chromaffin Cells

Lipid molecules such as arachidonic acid (AA) and sphingolipid metabolites have been implicated in modulation of neuronal and endocrine secretion. Here we compare the effects of these lipids on secretion from cultured bovine chromaffin cells. First, we demonstrate that exogenous sphingosine and AA i...

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Detalhes bibliográficos
Main Authors: García-Martínez, Virginia, Villanueva, José, Torregrosa-Hetland, Cristina J., Bittman, Robert, Higdon, Ashlee, Darley-Usmar, Victor M., Davletov, Bazbek, Gutiérrez, Luis M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779176/
https://ncbi.nlm.nih.gov/pubmed/24073281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075845
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