Stabilization of Kv4 protein by the accessory K(+) channel interacting protein 2 (KChIP2) subunit is required for the generation of native myocardial fast transient outward K(+) currents

The fast transient outward K(+) current (I(to,f)) underlies the early phase of myocardial action potential repolarization, contributing importantly to the coordinated propagation of activity in the heart and to the generation of normal cardiac rhythms. Native I(to,f) channels reflect the tetrameric...

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Hlavní autoři: Foeger, Nicholas C, Wang, Wei, Mellor, Rebecca L, Nerbonne, Jeanne M
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2013
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779109/
https://ncbi.nlm.nih.gov/pubmed/23713033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.255836
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