Memantine for the prevention of cognitive dysfunction in patients receiving whole-brain radiotherapy: a randomized, double-blind, placebo-controlled trial

BACKGROUND: To determine the protective effects of memantine on cognitive function in patients receiving whole-brain radiotherapy (WBRT). METHODS: Adult patients with brain metastases received WBRT and were randomized to receive placebo or memantine (20 mg/d), within 3 days of initiating radiotherap...

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Detalhes bibliográficos
Main Authors: Brown, Paul D., Pugh, Stephanie, Laack, Nadia N., Wefel, Jeffrey S., Khuntia, Deepak, Meyers, Christina, Choucair, Ali, Fox, Sherry, Suh, John H., Roberge, David, Kavadi, Vivek, Bentzen, Soren M., Mehta, Minesh P., Watkins-Bruner, Deborah
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Clinical Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779047/
https://ncbi.nlm.nih.gov/pubmed/23956241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not114
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