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Cells with intense EGFR staining and a high nuclear to cytoplasmic ratio are specific for infiltrative glioma: a useful marker in neuropathological practice

BACKGROUND: The differential diagnosis between infiltrative glioma (IG) and benign or curable glial lesions, such as gliosis, pilocytic astrocytoma, dysembryoplastic neuroepithelial tumor, ganglioglioma, or demyelinating disease, may be challenging for the pathologist because specific markers are la...

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Bibliographic Details
Main Authors: Burel-Vandenbos, Fanny, Turchi, Laurent, Benchetrit, Maxime, Fontas, Eric, Pedeutour, Zoe, Rigau, Valérie, Almairac, Fabien, Ambrosetti, Damien, Michiels, Jean-François, Virolle, Thierry
Format: Artigo
Language:Inglês
Published: Oxford University Press 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779042/
https://ncbi.nlm.nih.gov/pubmed/23935154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not094
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