Cells with intense EGFR staining and a high nuclear to cytoplasmic ratio are specific for infiltrative glioma: a useful marker in neuropathological practice

BACKGROUND: The differential diagnosis between infiltrative glioma (IG) and benign or curable glial lesions, such as gliosis, pilocytic astrocytoma, dysembryoplastic neuroepithelial tumor, ganglioglioma, or demyelinating disease, may be challenging for the pathologist because specific markers are la...

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Main Authors: Burel-Vandenbos, Fanny, Turchi, Laurent, Benchetrit, Maxime, Fontas, Eric, Pedeutour, Zoe, Rigau, Valérie, Almairac, Fabien, Ambrosetti, Damien, Michiels, Jean-François, Virolle, Thierry
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2013
Teme:
Basic and Translational Investigations
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779042/
https://ncbi.nlm.nih.gov/pubmed/23935154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not094
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