Cells with intense EGFR staining and a high nuclear to cytoplasmic ratio are specific for infiltrative glioma: a useful marker in neuropathological practice

BACKGROUND: The differential diagnosis between infiltrative glioma (IG) and benign or curable glial lesions, such as gliosis, pilocytic astrocytoma, dysembryoplastic neuroepithelial tumor, ganglioglioma, or demyelinating disease, may be challenging for the pathologist because specific markers are la...

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Hlavní autoři: Burel-Vandenbos, Fanny, Turchi, Laurent, Benchetrit, Maxime, Fontas, Eric, Pedeutour, Zoe, Rigau, Valérie, Almairac, Fabien, Ambrosetti, Damien, Michiels, Jean-François, Virolle, Thierry
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
Témata:
Basic and Translational Investigations
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3779042/
https://ncbi.nlm.nih.gov/pubmed/23935154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/not094
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