Chronic Intermittent Hypoxia Induces Atherosclerosis via Activation of Adipose Angiopoietin-like 4

Rationale: Obstructive sleep apnea is a risk factor for dyslipidemia and atherosclerosis, which have been attributed to chronic intermittent hypoxia (CIH). Intermittent hypoxia inhibits a key enzyme of lipoprotein clearance, lipoprotein lipase, and up-regulates a lipoprotein lipase inhibitor, angiop...

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Main Authors: Drager, Luciano F., Yao, Qiaoling, Hernandez, Karen L., Shin, Mi-Kyung, Bevans-Fonti, Shannon, Gay, Jason, Sussan, Thomas E., Jun, Jonathan C., Myers, Allen C., Olivecrona, Gunilla, Schwartz, Alan R., Halberg, Nils, Scherer, Philipp E., Semenza, Gregg L., Powell, David R., Polotsky, Vsevolod Y.
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778753/
https://ncbi.nlm.nih.gov/pubmed/23328524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201209-1688OC
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