The influence of prophylactic factor VIII in severe hemophilia A

INTRODUCTION: Hemophilia A individuals displaying a similar genetic defect have heterogeneous clinical phenotypes. AIM: To evaluate the underlying effect of exogenous factor (f)VIII on tissue factor (Tf)-initiated blood coagulation in severe hemophilia utilizing both empirical and computational mode...

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Main Authors: Gissel, Matthew, Whelihan, Matthew F, Ferris, Lauren A, Mann, Kenneth G, Rivard, Georges E, Brummel-Ziedins, Kathleen E
Format: Artigo
Language:Inglês
Published: 2011
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778653/
https://ncbi.nlm.nih.gov/pubmed/21899664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2516.2011.02638.x
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