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Anodic coupling of carboxylic acids to electron-rich double bonds: A surprising non-Kolbe pathway to lactones

Carboxylic acids have been electro-oxidatively coupled to electron-rich olefins to form lactones. Kolbe decarboxylation does not appear to be a significant competing pathway. Experimental results indicate that oxidation occurs at the olefin and that the reaction proceeds through a radical cation int...

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Autors principals: Perkins, Robert J, Xu, Hai-Chao, Campbell, John M, Moeller, Kevin D
Format: Artigo
Idioma:Inglês
Publicat: Beilstein-Institut 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778411/
https://ncbi.nlm.nih.gov/pubmed/24062822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.186
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