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Family-based association tests for sequence data, and comparisons with population-based association tests

Recent advances in high-throughput sequencing technologies make it increasingly more efficient to sequence large cohorts for many complex traits. We discuss here a class of sequence-based association tests for family-based designs that corresponds naturally to previously proposed population-based te...

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Hlavní autoři: Ionita-Laza, Iuliana, Lee, Seunggeun, Makarov, Vladimir, Buxbaum, Joseph D, Lin, Xihong
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3778346/
https://ncbi.nlm.nih.gov/pubmed/23386037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2012.308
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